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by LS Lemon 2024 Cited by 32First trimester ondansetron use is associated with an increased risk of neonatal VSD potentially driven by higher doses. This risk should be Lawsuits against pharmaceutical company GlaxoSmithKline claim that the use of anti-nausea medication Zofran during pregnancy can lead to birth defects. A recent study looked at women who had nausea and vomiting in pregnancy to see if taking Zofran is safe in pregnancy. Another possible reason could be the stress caused by HG during pregnancy. Maternal stress is a risk factor for long-term or irreversible Although it is not approved by the US Food and Drug Administration (FDA) for the treatment of nausea and vomiting in pregnancy, ondansetron is baby, ask your doctor or pharmacist for advice before taking Ondansetron. You should not use Ondansetron during the first trimester of pregnancy. This is Increased risk of oral clefts and ear malformations, however Mothers who took ondansetron (Zofran) in the first trimester of pregnancy were Serious side effects include QT prolongation and severe allergic reaction. It appears to be safe during pregnancy but has not been well studied in this group. Ondansetron (Zofran) is commonly and increasingly prescribed during pregnancy to relieve nausea. In 2024, an estimated 22 percent of

refnil it Another report, published in the journal Obstetrics Gynecology this year, found no increased risk associated with using ondansetron for nausea Key points Metoclopramide, domperidone and ondansetron are other medications that may be prescribed for nausea and vomiting and can be taken by mouth or by an Generally effective at reducing nausea and vomiting Considered safe for use in pregnancy by many healthcare providers ; Can cause side effects In general, experts say that taking Zofran during pregnancy is considered safe. The Zofran pregnancy category is B, per the U.S. Food and Drug Most studies show that ondansetron is safe to use during the first trimester when most women experience morning sickness. Talk to your doctor about when to take Zofran to treat severe morning sickness. Nausea during pregnancy usually begins at week 6 for many women Zofran Not FDA Approved For Use by Pregnant Women. Zofran was never approved by the FDA for use in pregnant women, yet this did not prevent the drug’s Taking Zofran during pregnancy is low risk. That said, Zofran for pregnancy nausea is an off-label use and may cause side effects. There might be better by T Taylor 2024 Cited by 26It is not recommended as first-line therapy, especially in the first trimester of pregnancy. Ondansetron commonly causes constipation, which

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